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10.1089/jmf.2018.0024 53 VerkerkR.TebbenhoffS.DekkerM.JuvikJ
While these can help with surface-level brightness and antioxidant protection, they often struggle to penetrate deep enough into the skin to affect melanin production at the source
Interestingly, while this study discovered that CHAC1/BOTCH-mediated regulation of GSH levels controls development, other studies suggest its developmental role is primarily based on the inhibition of NOTCH1 signaling (Yadav et al., 2019)
Ree, R., Varland, S
Briefly, mice were individually housed in standard laboratory cages
