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Lebers hereditary optic neuropathy, a rare genetic disorder affecting the optic nerve, has been associated with rapid optic atrophy following cyanocobalamin administration in some cases

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Some effects of the peptide are achieved through systemic antioxidant action and modulation of GABAergic, glutamatergic, and other neuronal systems

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Some physicians and patient advocates are concerned that the pursuit of lower Part B drug prices could endanger very sick Medicare Advantage patients if they can't be treated promptly with the medicine that was their doctor's first choice