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TLR pathway activation leads to secretion of pro-inflammatory cytokines, like interleukin (IL)-1, IL-6, and tumor necrosis factor-, as well as type 1 interferon

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Furthermore, chicken embryo lens epithelial cells stopped progressing through the cell cycle within 9 hours after lens rotation, indicating that suppression of lens cell proliferation at the initiation of fiber cell differentiation is dependent on factors from outside the lens