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Cell 126 , 177189 (2006)

4.2 Cervical cancer While most HPV infections are transient, a fraction persists and, over time, can initiate a carcinogenic cascade

Comparative studies could therefore provide valuable insight into species-specific oxidative mechanisms

it has a vital role in spermatogenesis and spermatozoon maturation [73,87], it inhibits viral infections (e.g., influenza) [88], it has an important role in the pathogenesis of different diseases such as cancer, inflammation, protein deficiency, Alzheimers disease, Parkinsons disease, hepatic diseases, cystic fibrosis, HIV, heart attacks, hemorrhagic stroke, diabetes, pulmonary disease, gastritis, duodenal ulcer, pancreatic disease, kidney disease, rheumatoid arthritis (RA), autoimmune thyroiditis, muscular dystrophy, amyotrophic lateral sclerosis, preeclampsia, cataract, glaucoma, atherosclerosis, and asthma [37,51,52,73,85,89,90,91,92,93,94,95,96]

The Nrf2/HO-1 pathway plays a critical role in cellular defense against oxidative stress (41)