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In the absence of light, PS at therapeutic concentrations typically exhibit minimal cytotoxicity, and light alone has no impact on the affected tissue
The highest stage of GAP (stage III) has been found to be associated with a 39% risk of mortality at 1 year
Neurons expressing Munc18-1 Q301R synapses showed a normal miniature EPSC (mEPSC) frequency, while Q301D showed a significantly lower frequency (Fig
Miao et al., 2010)
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