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Consequently, histone acetylation at distinct locations may assume disparate roles in diverse neuronal subtypes (e.g., DA, 5-HT, Glu neurons), offering novel insights into the intricate mechanisms underlying METH addiction

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The emergence of genotype-specific DAA resistance has led to an increase in demand for pangenotypic therapies that have a higher barrier to drug resistance (such as sofosbuvir/velpatasvir or glecaprevir/pibrentasvir) for treatment of all HCV genotypes, especially in resource-limited areas when genotype testing is unavailable