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Lancet Public Health 5, e661e671

However, early onset of AD can predominantly be diagnosed in patients with familial AD, due to mutations in the Amyloid Precursor Protein (APP), presenilin 1 (PSEN1) and presenilin 2 (PSEN2) genes (Piaceri et al., 2013

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As one of the most important steps of lipid metabolism, FAO and its key rate-limiting enzyme, the CPT system, regulate host immune responses, which is of great clinical significance
