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S.AladinskiyV

Of note, hemolysis is a fundamental feature of SCD and resulting excess hemin exposure 32 while hypoxia has been shown to induce the expression of fetal hemoglobin 33,34 , and promote the transition from expansion to differentiation during stress erythropoiesis 35
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408 Furthermore, its downregulation might reduce -catenin levels and cause a carcinogenic shift, 240 warranting further exploration of its therapeutic potential in redox control and Wnt signaling
