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The early activation of ion channels, kinase cascades, and PTMs indicates that stress signaling operates through a multilayered regulatory system capable of adjusting metabolism, gene expression, and protein stability within seconds to minutes of exposure

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Metabolic Reprogramming and Organ-Specific Metastasis Metabolic plasticity is one of the important characteristics that distinguishes the tumor cells with high metastatic potentiality from non-metastatic tumor cells

Persistent accumulation of damaged mitochondria due to impaired mitophagy is a likely antecedent to neurodegenerative disease

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