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Based on these observations, the first vaccination cycle was followed by a second prime-boost cycle 3 weeks later with 5 10 8 PFU of rMVA-EE2-MCP and 50 g of each antigen in the rEE2-rMCP-subunit boost vaccine, also 3 weeks apart

The peptide structure includes modifications that resist degradation by dipeptidyl peptidase-4 (DPP-4), an enzyme that rapidly breaks down natural GLP-1

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