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By contrast, BPC 157 largely interacts with the NO system in various models and species, as shown in cytoprotection studies, in particular, studies using both L-NAME and L-arginine as individual agents or in combination[2-4]

It has also been found to have an antidepressant effect 7

DOI: 10.1093/ndt/gfv409 57
The MTHFR enzyme is responsible for converting tetrahydrofolate into 5-methyltetrahydrofolate (5-MTHF), and reduced enzyme activity may influence methylation efficiency, particularly if riboflavin (vitamin B2) status is suboptimal

10.1016/j.ecoenv.2010.08.002 79 JoseM