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Pearson's correlation coefficient was used for distance measurements and average linkage (default) variance was used as the clustering method

Greco, and M

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Similar to the PDSS2 BKO mice, another study found that genetically engineering liver, adipose tissue, or skeletal muscle to secrete FGF21 using adeno-associated virus (AAV), prevented weight gain and insulin resistance associated with aging (Jimenez et al, 2018)
