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Pritam P et al (2022) Antioxidants in Alzheimers disease: current therapeutic significance and future prospects

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Evidence from clinical trials has validated riluzoles effectiveness in extending median survival of ALS patients by two to three months and slowing the decline in respiratory capabilities, a significant marker of ALS progression (25)

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324 YoshidaH.KongY

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XW, YH, FC, MW, and YX performed the experiments and acquired the data

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Mutations in the DLG motif disrupt the low-affinity binding of Keap1 with Nrf2, resulting in the stabilization of Nrf2, although the association between Keap1 and Nrf2 through the high-affinity binding site, ETGE, is retained

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