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[DOI] [PubMed] [Google Scholar] 66.Sloan J.L., Mager S

Mitochondrial mechanisms underlying antidepressant efficacy and future directions Considering that mitochondrial regulation is a key downstream mechanism involved in the pathophysiology of MDD, we summarize how conventional and rapid-acting antidepressants, as well as mitochondria-targeted compounds, modulate bioenergetics, oxidative defense, mitophagy, and neuroinflammatory signaling, and discuss their therapeutic implications and future directions (Fig

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