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Pernicious anemia tongue changes: I mentioned above in the symptoms that there could be changes to the tongue, called glossitis

[DOI] [PubMed] [Google Scholar] 158.Keizer H.G., Pinedo H.M., Schuurhuis G.J., Joenje H

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This vascular remodeling decreases elasticity, heightening peripheral resistance and blood pressure [186, 187]

It does this by activating the innate repair receptor (IRR), a heteromer of the EPO receptor and the beta-common receptor (CD131), which simultaneously triggers anti-inflammatory and tissue repair pathways