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The Human Gene Mutation Database (HGMD) contains 43 different GSS variants that have been reported as of January 2023, with missense variants showing predominance (55.8%), followed by splice variants (21.0%), small insertions/deletions (11.5%), large insertions/deletions (7.0%), and nonsense variants (4.7%)

Daily stress, poor diet, and lack of sleep are "withdrawals." Supplementation and healthy habits are "deposits." If you are constantly making withdrawals without any deposits, you eventually run into a deficit, which manifests as fatigue and poor sleep

Exclusion criteria included prior biologic therapy or documented history of PsA (ICD-10-CM code L40.5) before the index date

Never use bacteriostatic water past its labeled expiration date