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Key functions of IGF-1 include: Muscle growth & repair Stimulates protein synthesis and satellite cell activation for hypertrophy and recovery
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Serious events (organ toxicity, hormone suppression) have not been documented, but long-term safety data are lacking
184 But, in a preclinical study on the DMBA-induced rat mammary carcinoma, this enhanced effectiveness of methotrexate was far outweighted by the growth-stimulating effect of 3-day pretreatment with combined insulin/glucose infusions
[DOI] [PMC free article] [PubMed] [Google Scholar] 188.Drapier J.-C., Hibbs J.B
