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Effects of the garlic components diallyl sulfide and diallyl disulfide on arylamine Nacetyltransferase activity in human colon tumour cells

In cancer, glutamate receptor overexpression is linked with the activation of different signaling pathways including PI3K/AKT/mTOR, RasMAPKERK, and MAPK/ERK, which are involved in the regulation of cell proliferation, survival leading to tumorigenesis (43, 54, 55)

The cells were transfected with either siRNA1 HSPA1A or siRNA2 HSPA1A to knock down the expression of HSP70, and their sequences were listed in Supplementary Table 1

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