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Finally, both DFO and the glutaminolysis inhibitor Compound 968 prevent cell death in an ex vivo model of ischemia/reperfusion injury in the mouse heart [10]

10.1016/j.autrev.2020.102617 22

Consumption of the high glucose/highly glycated/increased AGEs diet shortens lifespan, reduces healthspan and promotes oxidative stress

39 Suppl 1, S20S33

Therefore, heterozygous carriers do not require treatment
