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(25) It was intended to clarify the need for selectivity in the clinic, but since toxicological studies did not reveal any major difference between cagrilintide 23 and NN1213, the development of NN1213 is currently on hold

Chronic tendinopathy this is where the actin-mediated rationale is most interesting in theory: chronic tendinopathy involves fibroblast dysfunction, and a cell-migration mechanism is proposed to address that differently than pure growth-factor approaches
Ethics declarations All experiments were carried out following the European Parliament and Council Directive 2010/63/EU and in compliance with the ARRIVE guidelines

doi: 10.1073/pnas.0537588100 228 ClaytonPEBanerjeeIMurrayPGRenehanAG

Hasanpour-Dehkordi A
