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Conversely, prostate cancer cell lines exhibit aberrant intracellular lipid metabolism [191], and an increased gene expression of glutaminolitic enzymes and glutamine transporters, thereby stimulating cell growth via glutamine uptake [192]

For example, patients with ornithine transcarbamylase deficiency, a rare inherited enzyme deficiency, also show reduced cerebral Glu metabolism however unlike CHE, Gln metabolism remained unchanged

Obesity and inflammation: the linking mechanism and the complications

doi: 10.1038/nature14344 28 FengKLiuJGongLYeTChenZWangYet al