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REDEFINE 2 was a double-blind, randomized, placebo- and controlled 68-week efficacy and safety phase 3 trial of once-weekly CagriSema versus placebo in 1,206 adults with type 2 diabetes and either obesity or overweight

Walking ability was scored (1-3) using a simple modification of the previous assessment as follows: 1 - normal walk, optimal speed, no tottering

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In laboratory research it is investigated for its effects on insulin signalling, glucose homeostasis and energy-balance pathways in experimental models