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In many chronic diseases, the concentration of glutathione in the body is significantly reduced [1]
Stage III
A recent paper using the zebrafish tailfin regeneration model demonstrated that Sonic hedgehog (Shh) a key signalling protein in the hedgehog signalling cascade acted downstream of NOX to increase SOD activity and H 2 O 2 production in the early stage of tailfin regeneration, most likely due to SOD oxidation 130
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