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doi: 10.1371/journal.pone.0050454 20 HeFRuXWenT

Reported reactions include: Reactive thrombocytosis Hypersensitivity: rash, pruritus, anaphylaxis Headache, paraesthesia, tremor Cardiac arrhythmias secondary to hypokalaemia Nausea, vomiting, diarrhoea Fever, chills, hot flushes, dizziness, malaise Injection site reactions: pain, erythema, pruritus, induration, swelling Acneiform and bullous eruptions Chromaturia (red/orange urine) Overdose Treatment is unlikely to be required

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The level of PC.aa.C42.4 was 1.9 times higher in PS-L skin compared to PS-NL skin (p = 0.0196) and the level of PC.aa.C40.4 was 1.5 times higher in PS-L skin compared to C (p = 0.0439)