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COPD is a highly heterogeneous disease, and its complex pathophysiological mechanisms and clinical manifestations pose significant challenges for clinical trial design

Federation of European Neuroscience Societies - FENS #alzheimers #MultipleSclerosis #sleep #NeurocognitiveDisorders #brain To view or add a comment, sign in Today, Im pleased to share our latest research exploring the real-world validity of genetic prediction for sleep traits in young adults

Approximately 40% of individuals with FHI do not have an identifiable mutation in any of the genes known to be associated with FHI

[DOI] [PMC free article] [PubMed] [Google Scholar] 312.Lapatto, H

Specifically, the IMS oxidoreductase Mia40, one of the two key components for the MIA pathway responsible for targeting many intermembrane space proteins, has been shown (both in vivo and in vitro) to bind to iron/sulfur clusters, in addition to its well-established role in mitochondria biogenesis [59, 60]