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Among various alkylating agents, N-ethylmaleimide is identified as the most reliable for thiol stabilization in liquid chromatographymass spectrometry (LC-MS) workflows, while specific reagents such as monobromobimane or -(4-hydroxyphenyl)ethyl iodoacetamide (HPE-IAM) are required for persulfide and polysulfide detection

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In line, a strain devoid of endogenous glutathione showed a more reducing periplasm, and was significantly worse in oxidatively folding PhoA, a native periplasmic protein and substrate of the oxidative folding machinery

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This study explores the use of a dual-sensitive alginate-coated mesoporous silica nanohybrid as a carrier for the enhanced delivery of polyphenols