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Description
As the deficiency of the cobalamin-intrinsic factor receptord affects the absorption of vitamin B12 from the ileum into the blood, patients respond well to parenteral vitamin B12 therapy, but not to oral vitamin B12 supplementation (3, 4)
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As for the different sex-related activities of metabolizing enzymes, the specific activity of the catabolic enzyme gamma-glutamyltranspeptidase in female mice was 73% of that in male mice, suggesting that the faster glutathione turnover in males could account for the higher susceptibility to oxidative injury [64]
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