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These gonad defects likely contribute to the reduced brood sizes in the mutant strains

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Mounjaro (tirzepatide) is a prescription medication licensed by the Medicines and Healthcare products Regulatory Agency (MHRA) for the treatment of type 2 diabetes mellitus in adults

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They showed that in ApoE/ mice, genistein supplementation reduced presenilin one mRNA and beta-secretase 1 level and beta-amyloid peptide (A) protein levels, but not in WT mice

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