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Description
Protocol adjustments Initial protocols sometimes need adjustment
The right doses
USA 109 , 1175811763 (2012)
Activation of necroptosis triggers the release of damage-associated molecular patterns (DAMPs), including high-mobility group box 1 (HMGB1), ATP, and nucleic acids, which promote dendritic cell maturation, tumor antigen presentation, and the activation of cytotoxic T cells
Yes, and this is common practice in the preclinical literature
