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By targeting distinct but interconnected pathways, this synergy could more effectively counteract the oxidative stress and inflammatory cascades that fuel colorectal tumorigenesis

Trabectedin, approved for the treatment of soft tissue sarcoma (STS), interferes with cell division and genetic transcription processes

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The catalase inhibitors used, 3-amino-1H-1,2,4-triazole (3-AT) and sodium azide (NaN3), inhibited the removal of hydrogen peroxide by bovine catalase at a high rate in in-vitro experiments