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Thickened ligaments can encroach on the spinal canal, which may contribute to narrowing and increase pressure on the surrounding nerves

Biochemistry 2006

So they would likely give you a similar cancer risk to a type 1 diabetic that has very high growth hormone
Tissue Distribution of and Species Differences in Deacetylation of N-Acetyl-L-Cysteine and Immunohistochemical Localization of Acylase I in the Primate Kidney
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