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doi: 10.1016/j.dld.2014.01.159 83 TofaloRCocchiSSuzziG

Cells lacking ETT are more susceptible to oxidative stress, resulting in increased mitochondrial DNA damage, protein oxidation and lipid peroxidation

Besides, ISL treatment not only effectively reduced TNF- and IL-6 gene expression in LPS-induced mouse primary peritoneal macrophages but also attenuated lung and liver injuries induced by LPS, accompanied by decreased inflammatory responses, which may be strongly related to NF-B inhibition (Yang et al., 2021b)

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2018;173(2):321337.e10