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Signalling mechanisms and cellular functions of SUMO

These findings underscore EGFR, GSK3B, and STAT3, for carbamazepine and PTGS2, mTOR, and TLR4 for valproic-acid as pivotal therapeutic targets in oxidative stress-associated epilepsy

A substrate side chain larger than glycine, alanine, or proline would likely clash with the loop spanning Asn-479 through Gly-483, suggesting that T-Mac likely prefers small amino acids after the cleavage position

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References Papers of particular interest, published recently, have been highlighted as: Of importance Of major importance 1.Farnum CE Postnatal growth of fins and limbs through endochondral ossification In Fins into limbs: evolution, development, and transformation
