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doi: 10.1038/mi.2015.18

Mechanistically, Chronic inhalation of asbestos fibers induces persistent pulmonary inflammation and fibrosis, which not only impairs gas exchange but also contributes to pulmonary vascular remodeling, ultimately leading to pulmonary hypertension

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Irregular menstrual cycles can be caused by any number of things, such as stress, weight loss, hormonal birth control, and hormonal changes that occur naturally, such as during menopause
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