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Despite this, current methods of visualizing these markers requires oocyte fixation rendering them unusable for use in artificial reproductive techniques

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doi: 10.1186/s12883-019-1500-6, 45

The metabolism of VPA can be affected by numerous factors including genetic variability in CYP450 enzymes, inborn errors of metabolism, concomitant use of other medications, malnutrition and inhibition of normal metabolic pathways during acute poisoning

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