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[24] Gfeller D, Grosdidier A, Wirth M, Daina A, Michielin O, Zoete V

Because CHE decreases patient quality of life, increases socioeconomic burden, and hastens mortality, it might be necessary to test and diagnose all patients at risk

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[85] [86] Approval status [edit] Off-label uses [edit] In 2012, pharmaceutical company Abbott paid $1.6 billion in fines to US federal and state governments for illegal promotion of off-label uses for Depakote, including the sedation of elderly nursing home residents