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Taking niacin in large amounts can also cause liver damage, which can be very serious
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MC: Writing original draft
Whether this is an alternative mechanism of action for this drug is unknown
Furthermore, ROS mediates the intrinsic apoptosis by promoting the release of proapoptotic factor cytochromec from mitochondria to form apoptosome with apoptotic protease activating factor 1 (APAF1) and caspase9 [151]
