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Similarly, triggering receptor expressed on myeloid cells (TREM) 2, a phospholipid sensing receptor, is expressed by microglia, sustains microglia activity, and mediates myelin debris consumption [200]

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In particular, H 2 O 2 promotes actin cytoskeleton reorganisation and cell migration by directly oxidising actin and actin-binding proteins 116 , as well as activating numerous cell signalling pathways associated with re-epithelialisation

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