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To investigate the mechanism of GSH dependent transport mediated by MRP1, we localized on the 3D structure of the transporter 40 two putative GSH binding sites deduced from the numerous mutagenesis studies done in the past two decades on MRP1 compiled in the database 50 , one located in the cytoplasmic face and the other located in the membrane (Fig

Medicube's phospholipid capsules mimic skin structure, so the glutathione reaches deeper layers where brightening is more effective

Disclosure The authors report no conflicts of interest in this work

doi: 10.1111/nph.19703 55 NjusD.KelleyP

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Juan C.A., Perez de la Lastra J.M., Plou F.J., Perez-Lebena E