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: Vitamin B12 administered 1mg/week intravenously for 3 months : IV supplementation with folinic acid 3mg plus B12 1mg intravenously for 3 months/week : Initially received cobalamin 1250 g per week for 2 months, orally, then received 15 mg folic acid daily for 8 weeks, orally

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Outcomes appear highly context-dependent, reinforcing the need for controlled experimental design and continued mechanistic research

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Since egr-1 is critical in proliferation, differentiation, and inflammation during cholestatic liver injury, cytokine and growth factor generation and early extracellular matrix (collagen) formation (Kim et al., 2006