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It is created when the hepatic flavin monooxygenases (FMOs

Kidney Disease Outcomes Quality Initiative

Am Rev Respir Dis 112(2):219249 Wu Z, Li M, Huang ACJ, Jia X, Li Y, Chen M (2009) Effects of serum containing natural cerebrolysin on glucose-regulated protein 78 and CCAAT enhancer-binding protein homologous protein expression in neuronal PC12 cells following tunicamycin-induced endoplasmic reticulum stress

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In humans it is synthesized in the liver, kidney, and brain and actively transported to other areas of the body