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The third pathway relies on the activity of ATF-6, the orthologue of activating transcription factor 6

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Deciphering lipid codes: K-Ras as a paradigm

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This suggests that active dimers are incompatible with formation of the repeating helical structure because the helical interaction interfaces are occluded by the presence of the other LPL subunit in the helical interface

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Khan et al., 2013)

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