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10.1016/j.toxlet.2016.10.016 146 YuY.XuJ.LiH.LvJ.ZhangY.NiuR.et al (2023)

Cell Metab 22(3):48598 [DOI] [PMC free article] [PubMed] [Google Scholar] 88.Cant C, Menzies KJ, Auwerx J
Both the GLS gene encoded enzymes and the GLS2 encoded enzymes require phosphate for activity
Although there are multiple effects as a result of an increase in ROS, an AOP calls for one specific path
Due to the strength of these doses, they require close monitoring to avoid saturation or unwanted detox responses
