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Differential gene expression analysis revealed that the P+ population uniquely upregulated 464 genes following LPS stimulation, whereas the P population upregulated 217 genes (Fig
Bioorg Med Chem 2003
See Table 2 for definitions
One possible explanation is that regeneration may require an initial period of type 1 inflammation, and that the anti-inflammatory effect of nicotine weakens the nerve regeneration
However, a randomized controlled trial ( N = 58) found no differences between GR + myrosinase (100 mol SF per day for 16 weeks) treatment and placebo groups in PANSS scores and cognitive functioning among individuals with schizophrenia (48)
