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On the other hand, oxidative mtDNA is released into the cytoplasm due to the elevated MMP, triggering innate immune responses, such as NLRP3 activation, and subsequently leading to the upregulation of inflammatory factors like IL-1 [16]

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Baltimore: Williams & Wilkins, pp: 941-964

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PMID 27753690

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The Nomenclature Committee on Cell Death (NCCD) classifies cell death into two broad categories based on functional and mechanistic criteria: accidental cell death (ACD), a passive process, and regulated cell death (RCD), an active, gene-controlled mechanism ( Ferroptosis, first identified and described by Dixon et al

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An N-acetyl cysteine ruthenium tricarbonyl conjugate enables simultaneous release of CO and ablation of reactive oxygen species

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