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Description
Antioxidant Defenses in the Human Eye: A Focus on Metallothioneins
These results are compatible with the idea that, in response to glucose, NNT produces NADPH which, through a regulation of E GSH , amplifies exocytosis [8, 9, 35]
Their injurious properties are manifested through different mechanisms, most notably peroxidative DNA damage, the induction of apoptosis, and lipid peroxidation [21]
2023;9:eadg2697
Therefore, results from clinical trials are expected to provide a better understanding of the pharmacokinetics and pharmacodynamics of cereblon-based PROTACs and guide future optimization of their design and development
