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Med Clnica Prctica (2019) 2(6):1058

The selenium content in brazil nuts varies dramatically depending on where they were grown, so you cannot rely on a consistent dose from nuts alone

These findings were corroborated by the study in which genetic depletion of astrocytes from cuprizone-induced demyelination model resulted in impaired microglia recruitment and consequent delay in the clearance of myelin debris and in remyelination (106)

In particular, the highly polyunsaturated docosahexaenoic acid shows a protective effect against AD in model systems, not only because of its ability to affect membrane fluidity but also by serving as a substrate for the formation of pro-survival and anti-inflammatory products (Hashimoto et al., 2011