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The end-result of SCD1 inhibition may, therefore, be an aggravation of NASH due to intracellular accumulation of cytotoxic saturated fatty acids [51, 62], placing the partitioning of saturated fatty acids to mono-unsaturated fatty acids as a protective factor in delaying NAFLD progression

Moreover, several plastid enzymes involved in reactive oxygen species (ROS) scavenging and damage repair draw electrons from glutathione

For dietary supplements, typical doses range from 250-1000mg daily

10.1155/2019/4189813 23 EftekharpourE.FernyhoughP

[DOI] [PMC free article] [PubMed] [Google Scholar] 91.He H., Wang S., Tian J., Chen L., Zhang W., Zhao J., Tang H., Zhang X., Chen J