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While TRT has demonstrated benefits like increased energy, libido, and muscle mass in hypogonadal men, some concerns remain about long-term safety, especially prostate effects, based on the lack of large, multi-year studies
GHK-Cu also has strong topical relevance in peptide and cosmetic research, although published work notes that skin absorption can be limited without delivery support

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Results showed that the control group had the highest degree of epidermal incompleteness, while the wounds in the hydrogel groups showed varying degrees of epidermalization

Therefore, only in rare occasions a substance is included in S0 after a case-by-case evaluation
