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doi: 10.3389/fnagi.2025.1495769 Received 13 September 2024 Accepted 28 March 2025 Published 09 May 2025 Volume 17 - 2025 Edited by Ramesh Kandimalla, Indian Institute of Chemical Technology (CSIR), India Reviewed by Chunchen Xiang, Capital Medical University, China Bruno piljak, University of Zagreb, Croatia Updates Copyright 2025 Li, Zhang, Yu, Xue and Hu

A typical GST reaction involving xenobiotics results in the conjugation of the toxic substrate to form an S -glutathionylated reaction product (Figure 6a)

Early on, it can be difficult to distinguish between MSA and PD because the symptoms are frequently asymmetrical and some individuals respond well to levodopa medication at first

a) major findings from transcriptional studies

10.1038/nature12751 Nature 50 HerranzD.Muoz-MartinM.CaameroM.MuleroF.Martinez-PastorB.Fernandez-CapetilloO.et al (2010)
